Hepatic Iron Quantification

SUMMARY

If the iron quant ROI measured 600, the R2* value would be 600 Hz and you would do 1000/600 as described below for a T2* time of ~2ms, which is normal.

A quick way to do fat fraction from MR physics is:

In phase - out of phase/ (2 x in phase)

In this case, in phase was 400, out of phase 200 =

400-200/(2X400) = 0.25

Fat fraction is 25%

click HERE to download Wood et al 2005 Blood article on MRI R2 and R2* mapping to estimate hepatic iron concentration

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